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Mean Corpuscular Hemoglobin (MCH), Mean Cell Hemoglobin

Mean Corpuscular Hemoglobin (MCH), Mean Cell Hemoglobin
September 22, 2020HematologyLab Tests

Sample

  • This test is done on blood in EDTA (anticoagulant).

Indication

  1. It is done as part of blood indices.
  2. It is done to diagnose anemia.

Precaution

  1. Keep in mind that the abnormal size of the RBC may affect the value.
  2. The presence of cold agglutinins gives false raised value.
  3. Raised WBC count also affects the value.

Pathophysiology

  1. This is the mean of the weight of average hemoglobin in one RBC.                                                   
Calculation formula for MCH

The calculation formula for MCH

  1. MCH and MCHC values are used to determine the contents of hemoglobin in the RBCs.
  2. MCH adds very little value to other blood indices.

NORMAL

Source 1

Age pg/cell
Fetal blood
18 to 20 weeks 43.14 ± 2.7
21 to 22 weeks 41.39 ± 3.32
23 to 25 weeks 40.48 ± 2.88
26 to 30 weeks 37.04 ± 3.67
Infants and Child
Cord blood 31 to 37
0.5 month 30 to 37
0ne month 29 to 36
2 month 27 to 34
4 month 25 to 32
6 month 24 to 30
9 month 25 to 30
12 month 24 to 30
1 to 2 year 22 to 30
3 to 5 year 25 to 31
6 to 8 year 25 to 31
9 to 11 year 26 to 32
Male  Female
12 to 14 year 26 to 32 26 to 32
15 to 17 year 27 to 32 26 to 34
18 to 44 year 27 to 37 27 to 34
45 to 64 year 27 to 35 27 to 34
65 to 74 year 27to 34 27 to 35


Source 2

  • Adult = 27 to 31 pg (picogram).
  • Newborn = 32 to 34 pg (picogram)

Increased MCH is seen in:

  • Macrocytic anemia and in newborn.
    Macrocytes Red blood cell

    Macrocytes Red blood cell

Decreased MCH is seen in:

  • Microcytic anemia.
  • Hypochromic anemia.
Microcytic Red Blood Cell

Microcytic Red Blood Cell


Possible References Used
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