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Doctor Patient relationship By Prof. WB Sajid

Posted April 24, 2016. Psychiatry

Doctor-Patient Relationship by Prof. WB Sajid. Can contact the author on Phone +923005118688


Genetic and Biochemistry of behaviour By Prof. WB Sajid

Posted April 24, 2016. Psychiatry

Genetics and Biochemistry of Behavior by Prof. WB Sajid. Can contact the author on Phone +923005118688


Introduction to BHS By Prof. WB Sajid

Posted April 24, 2016. Psychiatry

Introduction to BHS by Prof. WB Sajid. Can contact the author on Phone +923005118688



Stress Management By Prof.WB Sajid

Posted April 24, 2016. Psychiatry

Stress Management by Prof. WB Sajid. Can contact the author on Phone +923005118688


Personality By Prof. WB Sajid

Posted April 24, 2016. Psychiatry

Personality  by Professor WB Sajid. Can contact the author on Phone +923005118688


Lecture on Ulcerative Colitis and Crohn's Disease

Posted Nov. 3, 2014. Pathology

Ulcerative Colitis  is an inflammatory bowel disease (IBD) that affects the large intestine (colon and rectum). Ulcerative colitis affects the only the large intestine.

Crohn’s disease is inflammatory bowel disease. While Crohn’s can affect any part of the gastrointestinal (GI) tract from mouth to anus, 

Ulcerative colitis is considered to be the autoimmune disease. This is due to inflammation caused by the immune system and mainly occurs in the large intestine.

Following are the signs and symptoms of Ulcerative colitis.

  1. Diarrhea, often with blood or pus
  2. Abdominal pain and cramping
  3. Rectal pain
  4. Rectal bleeding , there is  passing small amount of blood with stool
  5. Urgency to defecate
  6. Inability to defecate despite urgency
  7. Weight loss
  8. Fatigue
  9. Fever
  10. In children, failure to grow

Crohn's disease cause is unknown.Diet and stress were suspected, but now doctors know that these factors may aggravate but don't cause Crohn's disease. A number of factors, such as heredity and a malfunctioning immune system, likely play a role in its development.

Following are the main signs ans symptoms of the active Crohn's disease.

  1. Diarrhea with cramps.
  2. Fever and fatigue.
  3. Abdominal pain and cramping.
  4. Blood seen in the stools.
  5. Mouth ulcers.
  6. There is decrease in the appetite.
  7. There is weight loss.
  8. There is involvement of the perianal area.
Comparison table

Pathologic findings

              Ulcerative colitis                 Crohn's disease                                
Location
   
Ileum                       --                                      ++
Rectum                      ++                    + --
Skip lesion                      --                    +
Continuous involvement of colon                      ++

                  --

Involvement of Ileum

                     --                      ++
Gross appearance
                                    
Broad based ulcers                    ++                      --
Strictures                  + --                     ++
Fissures                   + --                     ++
Fistulas                  + --                     ++
Cobblestone appearance (mucosa)                  --                     ++
Pseudopolyp                  ++                     --
Microscopic appearance
   
Crypt abscess                  ++                       --
Granuloma formation                 --                    ++
Lymphoid aggregates                 --                     ++
Fibrosis of the wall                 --                     ++
Transmural involvement                  --                      ++